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J Am Acad Orthop Surg, Vol 14, No 10, September 2006, S145-S151.
© 2006 the American Academy of Orthopaedic Surgeons
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Accelerated Fracture Healing

J. Edward Puzas, PhD, Jeff Houck, PhD and Susan V. Bukata, MD

Dr. Puzas is Professor, Department of Orthopaedics, University of Rochester School of Medicine and Dentistry, Rochester, NY. Dr. Houck is Associate Professor, Department of Physical Therapy, Ithaca College, Ithaca, NY. Dr. Bukata is Assistant Professor, Department of Orthopaedics, University of Rochester School of Medicine and Dentistry.

None of the following authors or the departments with which they are affiliated has received anything of value from or owns stock in a commercial company or institution related directly or indirectly to the subject of this article: Dr. Puzas, Dr. Houck, and Dr. Bukata.

Acceleration of the fracture healing process would have far-reaching benefits for both civilians and military personnel. Decreasing the time to return to complete function would reduce medical costs, enhance quality of life by decreasing pain and increasing mobility, accelerate the return of professional athletes to their sport, and decrease the time for military recruits to enter active duty after injuries incurred in basic training. Moreover, augmenting the healing process may prevent the long-term disability caused by fracture nonunion. Currently available pharmaceutical agents may allow us to realize this goal. However, these agents need to be tested in prospective randomized clinical trials.






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Copyright © 2006 by the American Academy of Orthopaedic Surgeons.