© 2007 the American Academy of Orthopaedic Surgeons Amniotic Band Syndrome of the Upper Extremity: Diagnosis and ManagementDr. Moran is Associate Professor, Orthopaedic and Plastic Surgery, Mayo Clinic College of Medicine, Rochester, MN. Dr. Jensen is Resident, General Surgery, Mayo Clinic. Dr. Bravo is Co-Director, Microvascular, Hand and Upper Extremity Section, Carilion Clinic Bone and Joint Center, Roanoke, VA. None of the following authors or the departments with which they are affiliated has received anything of value from or owns stock in a commercial company or institution related directly or indirectly to the subject of this article: Dr. Moran, Dr. Jensen, and Dr. Bravo. Reprint requests: Dr. Moran, Mayo Clinic, Mayo 1244 West, 200 First Street SW, Rochester, MN 55905. Amniotic band syndrome, a condition involving fetal entrapment in strands of amniotic tissue, causes an array of deletions and deformations. Band formation most frequently affects the distal segments, including the hand. Because of the heterogeneous nature of expression of this disease, treatment is individualized. Timing of repair and surgical planning are important in improving functional outcome. In the patient with distal edema and acrosyndactyly, early repair portends better prognosis. Improvements in prenatal diagnosis and fetoscopic surgical technique may eventually allow treatment of amniotic band syndrome in utero.
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