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Paget's Disease of Bone: Pathophysiology, Diagnosis, and Management

FS Kaplan and FR Singer

Division of Metabolic Bone Diseases and Molecular Orthopaedics, University of Pennsylvania School of Medicine, Philadelphia.

Paget's disease of bone is a common geriatric disorder of skeletal remodeling, which may have a viral etiology. Safe and effective treatments are now available for associated complications of symptomatic involvement. The orthopaedic surgeon should have a fundamental understanding of the complications of Paget's disease and should be familiar with the indications for treatment, as well as available medical and surgical therapies.






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