JAAOS
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

J Am Acad Orthop Surg, Vol 8, No 4, July/August 2000, 243-252.
© 2000 the American Academy of Orthopaedic Surgeons
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lee, S. K.
Right arrow Articles by Wolfe, S. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lee, S. K.
Right arrow Articles by Wolfe, S. W.

Peripheral Nerve Injury and Repair

Steve K. Lee, MD and Scott W. Wolfe, MD

Dr. Lee is Major, United States Air Force, Section of Orthopaedic Surgery, Walson Air Force Hospital, Fort Dix, NJ. Dr. Wolfe is Professor and Director, Hand and Upper Extremity Center, Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, New Haven, Conn.

Reprint requests: Dr. Wolfe, Department of Orthopaedics and Rehabilitation, Yale University School of Medicine, 800 Howard Avenue, New Haven, CT 06510.

Peripheral nerve injuries are common, and there is no easily available formula for successful treatment. Incomplete injuries are most frequent. Seddon classified nerve injuries into three categories: neurapraxia, axonotmesis, and neurotmesis. After complete axonal transection, the neuron undergoes a number of degenerative processes, followed by attempts at regeneration. A distal growth cone seeks out connections with the degenerated distal fiber. The current surgical standard is epineurial repair with nylon suture. To span gaps that primary repair cannot bridge without excessive tension, nerve-cable interfascicular autografts are employed. Unfortunately, results of nerve repair to date have been no better than fair, with only 50% of patients regaining useful function. There is much ongoing research regarding pharmacologic agents, immune system modulators, enhancing factors, and entubulation chambers. Clinically applicable developments from these investigations will continue to improve the results of treatment of nerve injuries.




This article has been cited by other articles:


Home page
 JBJSHome page
J. C. Elfar, J. A. Jacobson, J. E. Puzas, R. N. Rosier, and M. J. Zuscik
Erythropoietin Accelerates Functional Recovery After Peripheral Nerve Injury
J. Bone Joint Surg. Am., August 1, 2008; 90(8): 1644 - 1653.
[Abstract] [Full Text] [PDF]

Home page
 JAOA: Journal of the American Osteopathic AssociationHome page
M. D. Kelly
Traumatic Neuralgia From Pressure-Point Strikes in the Martial Arts: Results From a Retrospective Online Survey
J Am Osteopath Assoc, June 1, 2008; 108(6): 284 - 287.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
M. S. Damaser, M. K. Samplaski, M. Parikh, D. L. Lin, S. Rao, and J. M. Kerns
Time course of neuroanatomical and functional recovery after bilateral pudendal nerve injury in female rats
Am J Physiol Renal Physiol, November 1, 2007; 293(5): F1614 - F1621.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2000 by the American Academy of Orthopaedic Surgeons.